The Caribbean region coast extends from the Gulf of Urabá to the Gulf of Venezuela. Straddling the coast are Colombia's two main Atlantic port cities of Barranquilla and Cartagena.
It can blow really hard, especially along the northern half of the coast and especially during January into April. It is a very bad idea to try to travel these waters on a tight schedule. But all year long, at least once every ten or 12 days, the near-shore winds let up for two to four days at a time, producing manageable, in fact enjoyable, sailing. From May to September almost the entire southwest Caribbean Basin has long periods with much convection and little or no near-shore wind and you can motorsail in almost any direction you choose. Early fall can provide occasional strong westerlies interspersed with calm periods. In the event of a really strong westerly wind, get into a protected anchorage or get offshore. As a general rule, winds and waves are lower very close (less than five miles) to shore. With a relaxed schedule and the assistance of custom weather information, such as provided by Chris Parker, it is quite reasonable to expect to be able to be entirely non-heroic while cruising along the entire Colombian coast.